Certified Clinical Transplant Nurse (CCTN) Practice Exam

Burkitt's lymphoma is the cancer most commonly associated with Epstein-Barr Virus (EBV) in transplant recipients due to the virus's role in the oncogenesis of this particular type of lymphoma. EBV is known to be an oncogenic virus and can lead to multiple malignancies, particularly in immunocompromised individuals, such as organ transplant recipients who are on immunosuppressive therapy.

In the context of transplant recipients, the suppressed immune response can result in unchecked proliferation of B cells leading to the development of lymphoproliferative disorders, including Burkitt's lymphoma. This aggressive form of non-Hodgkin lymphoma is characterized by rapid growth and is often linked to EBV in patients who are either HIV positive or immunocompromised.

While the other options may involve different mechanisms or associations with cancer, they are not as closely related to EBV in the context of transplant recipients. For instance, basal cell carcinoma is more associated with UV radiation and is less influenced by viral etiology. Melanoma also primarily relates to environmental factors and does not have a strong connection to EBV. Colorectal cancer is influenced by genetic and dietary factors rather than viral factors. Thus, Burkitt's lymphoma stands out as the