Certified Clinical Transplant Nurse (CCTN) Practice Exam

Question: 1 / 400

Which area of the body do Alpha-1 receptor drugs primarily affect?

Heart

Lungs

Arteries

Alpha-1 receptor drugs primarily affect the arteries. These drugs are adrenergic agonists that bind to alpha-1 adrenergic receptors, which are predominantly located on the smooth muscle cells lining blood vessels. When stimulated, these receptors lead to vasoconstriction, resulting in an increase in vascular resistance and blood pressure.

Understanding this action is crucial, particularly in the context of managing conditions such as hypertension and shock, where enhancing vascular tone can be beneficial. The focus on arterial systems highlights the role that alpha-1 receptors play in modulating vascular dynamics, which distinguishes them from other adrenergic receptors that influence heart rate or bronchial dilation.

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